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Prekallikrein Heavy Chain Antibody (OAQA00823)
เพิ่มเมื่อ: 2017-01-20 13:08:02.0
รายละเอียด:
AVV-OAQA00823
AVV-OAQA00823
- TypeMonoclonal Antibody
- SpecificityThis antibody specifically recognizes in human plasma two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). It also recognizes prekallikrein and its activation products in chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
- Host
- ApplicationELISA, WB
- CompanyAVIVA
- Catalog No.AVV-OAQA00823
- Product namePrekallikrein Heavy Chain Antibody (OAQA00823)
- IsotypeIgG1
- Size200 ug
- LinkDataSheethttp://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAQA00823
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Catalog No.
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AVV-OAQA00823
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Product Name
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Prekallikrein Heavy Chain Antibody (OAQA00823)
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Company
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AVIVA
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Type
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Monoclonal Antibody
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Size
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200 ug
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Isotype
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IgG1
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Application
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ELISA, WB
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Specificity
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This antibody specifically recognizes in human plasma two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). It also recognizes prekallikrein and its activation products in chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
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Product URL
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