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Estrogen Receptor-beta Antibody (OAQA00453)

 เพิ่มเมื่อ: 2017-01-20 11:33:46.0

รายละเอียด:
AVV-OAQA00453
  • TypeMonoclonal Antibody
  • SpecificityThis antibody recognizes human ER-beta, a novel receptor (approx. 52 kD) recently isolated from testis. The size and structure of ER-beta are very similar to ER- alpha with the ligand and DNA binding domains being highly conserved. The N-terminus of each receptor, which serves as their transactivation domain, are significantly different. Like ER- alpha , ER-beta binds to estrogen with a high affinity and regulates estrogen-specific gene activation through direct interaction with estrogen response elements.
  • Host
  • ApplicationWB
  • CompanyAVIVA
  • Catalog No.AVV-OAQA00453
  • Product nameEstrogen Receptor-beta Antibody (OAQA00453)
  • IsotypeIgG2b/kappa
  • Size100 ug
  • LinkDataSheethttp://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAQA00453
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Catalog No.
AVV-OAQA00453
Product Name
Estrogen Receptor-beta Antibody (OAQA00453)
Company
AVIVA
Type
Monoclonal Antibody
Size
100 ug
Isotype
IgG2b/kappa
Application
WB
Specificity
This antibody recognizes human ER-beta, a novel receptor (approx. 52 kD) recently isolated from testis. The size and structure of ER-beta are very similar to ER- alpha with the ligand and DNA binding domains being highly conserved. The N-terminus of each receptor, which serves as their transactivation domain, are significantly different. Like ER- alpha , ER-beta binds to estrogen with a high affinity and regulates estrogen-specific gene activation through direct interaction with estrogen response elements.
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Data Sheet

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