Catalog No.
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AVV-OAQA00453
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Product Name
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Estrogen Receptor-beta Antibody (OAQA00453)
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Company
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AVIVA
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Type
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Monoclonal Antibody
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Size
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100 ug
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Isotype
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IgG2b/kappa
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Application
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WB
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Specificity
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This antibody recognizes human ER-beta, a novel receptor (approx. 52 kD) recently isolated from testis. The size and structure of ER-beta are very similar to ER- alpha with the ligand and DNA binding domains being highly conserved. The N-terminus of each receptor, which serves as their transactivation domain, are significantly different. Like ER- alpha , ER-beta binds to estrogen with a high affinity and regulates estrogen-specific gene activation through direct interaction with estrogen response elements.
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Product URL
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สินค้าที่เกี่ยวข้อง
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