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BMF Antibody - C-terminal region (OAQA00122)
เพิ่มเมื่อ: 2017-01-20 11:29:36.0
รายละเอียด:
AVV-OAQA00122
AVV-OAQA00122
- TypePolyclonal Antibody
- SpecificityThis antibody recognizes an epitope at the C-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiaing the downstream apoptotic program. Bmf is constitutively expressed in many tissues.
- Host
- Application
- CompanyAVIVA
- Catalog No.AVV-OAQA00122
- Product nameBMF Antibody - C-terminal region (OAQA00122)
- Isotype
- Size100 ug
- LinkDataSheethttp://www.avivasysbio.com/sd/tds/html_datasheet.php?sku=OAQA00122
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Catalog No.
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AVV-OAQA00122
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Product Name
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BMF Antibody - C-terminal region (OAQA00122)
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Company
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AVIVA
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Type
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Polyclonal Antibody
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Size
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100 ug
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Isotype
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Application
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Specificity
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This antibody recognizes an epitope at the C-terminus of human Bmf (Bcl-2-Modifying Factor), a novel BH3-only protein. In healthy cells, Bmf associates with the dynein light chain 2 component of the myosin V motors and is sequestered by the cell's actin cytoskeleton. Disruption of the actin cytoskeleton, either by depolymerization of actin filaments or by detachment of cells from the extracellular matrix, triggers release and activation of Bmf, initiaing the downstream apoptotic program. Bmf is constitutively expressed in many tissues.
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Product URL
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